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For example, 45% of patients treated with divalproex sodium had a 50% reduction in complex partial seizure rate compared to 23% of patients treated with placebo

The list price for oral semaglutide without insurance has historically been around $1,000 per month, though Novo Nordisk announced significant price reductions of up to 50% in early 2026

Importantly, the Sema + -MSTN/-ActA group which had similar body weight reduction but increased lean mass compared to Sema alone also had markedly greater losses in fat mass, almost twice that seen with Sema alone (Fig