Histone H3 (Mono Methyl Lys79) Monoclonal Antibody(5G5), 20ul General Lab Use Mutations in MBTPS2 have been

Mutations in MBTPS2 have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome)

Mutations in FMN2 have been associated with mental retardation autosomal recessive 47 (MRT47)

its substrate has not yet been determined

CERKL was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease

and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration

Histone H3 (Mono Methyl Lys79) Monoclonal Antibody(5G5), 20ul General Lab Use Mutations in MBTPS2 have beenHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin