Nordihydroguaiaretic acid - CAS# 500-38-9 481585 wakefulness

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Formula: C20H32ClN3O

Chemical Name: (Z)-ethyl 4-(4-((5-nitrofuran-2-yl)methylene)-3

Nepafenac inhibits prostaglandin synthesis in the iris/ciliary body (85-95%) and the retina/choroid (55%) in rabbits

Target: Histamine H1-receptorMizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis)

Nordihydroguaiaretic acid - CAS# 500-38-9 481585 wakefulnessEtrasimod, also known as APD334, is a potent, centrally available, functional antagonists of the S1P1 receptor for use as next generation therapeutics for treating multiple sclerosis (MS) and other autoimmune diseases. APD334 has a favorable PK PD profile, producing robust lymphocyte lowering at relatively low plasma concentrations in several preclinical species. APD334 was efficacious in a mouse experimental autoimmune encephalomyelitis (EAE) model