TH 1020 Size:2mg solid Adavivint (SM04690) is a potent

Adavivint (SM04690) is a potent and selective inhibitor of Wnt signaling

This agent also inhibits other tyrosine kinases including those associated with vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs)

thereby blocking their deubiquitylating activity

at IC50s of 15

InChiKey: OCDGBSUVYYVKQZ-UHFFFAOYSA-N

TH 1020 Size:2mg solid Adavivint (SM04690) is a potentTH1020 is Toll like receptor (TLR) 5 Flagellin complex antagonist with IC50 of 0. 85 M. TH1020 competes with flagellin for TLR5 binding to inhibit the TLR5: flagellin interaction and subsequent downstream TNF secretion. Product information CAS Number: 1841460 82 9 Molecular Weight: 453. 54 Formula: C23H15N7S2 Chemical Name: 4 ((4 Benzyl 5 (pyridin4yl) 4H 1,2,4 triazol 3 yl)thio)pyrido[3',2': 4,5]thieno[3,2 d]pyrimidine Smiles: