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J Ginseng Res 42:264269

doi: 10.1136/bmjdrc-2022-002880

This immune response is partly why you feel so wiped out and foggy-headed

Mast cell activation and degranulation are followed by immune activation, for instance, the recognition of LPS by toll-like receptors or by IgE receptor activation

Using cellular models (liver cancer-derived), the study showed that vorinostat reduces HIF-1 protein levels under hypoxic conditions, leading to impaired hypoxia-responsive gene expression (203)