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In silico modeling and experimental validation confirm a prominent role of C8 for dimer formation and aggregation

Since GSH is the final product of the homocysteine metabolism in the transsulfuration pathway by transferring sulfur from homocysteine to cysteine, a deficiency in transsulfuration pathway leads to excessive homocysteine production (hyperhomocysteinemia) and reduced GSH synthesis (159, 160)

Therefore, while it is highly effective, it lacks the receptor-specificity that peptide secretagogues like Ipamorelin and Sermorelin offer

Cell viability was quantified using the Cell Counting Kit-8 (CCK8) assay

For a research protocol using a localized approach, the injection would typically be subcutaneous or shallow intramuscular