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Eletriptan hydrobromide - CAS# 177834-92-3 Catalog No.:M10984-2 JX06 (1-10 μM

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Eletriptan hydrobromide - CAS# 177834-92-3 Catalog No.:M10984-2 JX06 (1-10 μMEletriptan Hydrobromide is a triptan with specific affinity for the 5 hydroxytriptamine1B 1D receptor. Eletriptan hydrobromide binds to and acts at serotonin 5 HT1B receptors located on intracranial blood vessels which leads to vasoconstriction. This drug may also exert its effects by binding to and activating 5 HT 1D receptors on sensory nerve endings in the trigeminal system, which results in the inhibition of pro inflammatory neuropeptide release.

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Description

JX06 (1-10 μM

4R)-4-benzyl-2-hydroxy-4-{[(1S

Solubility: DMSO: 77 mg/mL (185

Wogonin (0-200 μM) exhibits a dose- and time- dependent reduces in cell viability of caco-2

Solubility: DMSO: 50 mg/mL(196

Eletriptan hydrobromide - CAS# 177834-92-3 Catalog No.:M10984-2 JX06 (1-10 μMEletriptan Hydrobromide is a triptan with specific affinity for the 5 hydroxytriptamine1B 1D receptor. Eletriptan hydrobromide binds to and acts at serotonin 5 HT1B receptors located on intracranial blood vessels which leads to vasoconstriction. This drug may also exert its effects by binding to and activating 5 HT 1D receptors on sensory nerve endings in the trigeminal system, which results in the inhibition of pro inflammatory neuropeptide release.

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