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Tazarotene - CAS# 118292-40-3 Size:Solid 2 mg InChiKey: ZFGXZJKLOFCECI-UHFFFAOYSA-N

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Tazarotene - CAS# 118292-40-3 Size:Solid 2 mg InChiKey: ZFGXZJKLOFCECI-UHFFFAOYSA-NTazarotene is a third generation prescription topical retinoid. Tazarotene is a retinoid prodrug which is converted to its active form, the cognate carboxylic acid of tazarotene, by rapid deesterification in animals and humans. Tazarotenic acid binds to all three members of the retinoic acid receptor (RAR) family: RAR, RAR, and RAR but shows relative selectivity for RAR, and RAR and may modify gene expression. Product information CAS Number: 118292 40

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Description

InChiKey: ZFGXZJKLOFCECI-UHFFFAOYSA-N

Mg/c1-13-39-34(7)41-29-46-48(38(11)60)36(9)43(57-46)27-42-35(8)40(52(58-42)50-51(55(63)64-12)54(62)49-37(10)44(59-53(49)50)28-45(39)56-41)23-24-47(61)65-26-25-33(6)22-16-21-32(5)20-15-19-31(4)18-14-17-30(2)3

inducing selective G2/M cell-cycle arrest followed by apoptosis in a variety of tumor cells while causing reversible cell-cycle arrest at the G1 and G2 stages without apoptosis in normal cells

CAS Number: 4079-26-9

1 μM S-(+)-Rolipram significantly antagonizes ovalbumin (OA) induced concentration-related contractions of tracheal rings which are isolated from OA-sensitized guinea pigs

Tazarotene - CAS# 118292-40-3 Size:Solid 2 mg InChiKey: ZFGXZJKLOFCECI-UHFFFAOYSA-NTazarotene is a third generation prescription topical retinoid. Tazarotene is a retinoid prodrug which is converted to its active form, the cognate carboxylic acid of tazarotene, by rapid deesterification in animals and humans. Tazarotenic acid binds to all three members of the retinoic acid receptor (RAR) family: RAR, RAR, and RAR but shows relative selectivity for RAR, and RAR and may modify gene expression. Product information CAS Number: 118292 40

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