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Before making the diagnosis of PFIC, in the paediatric population, other cholestasis disorders should always be considered in the differential diagnosis, including biliary atresia, choledochal malformations, congenital endocrine disorders, inborn errors of metabolism (mainly during the neonatal period) as well as autoimmune liver diseases, drug-induced cholestasis and other genetic diseases in older children [72]

At that stage the impact of liraglutide on weight loss was fairly small, averaging a few percent per person (Mller, Preker)

Protein and resistance training matter here, and well get to that next

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