The prudent framing is that systemic copper delivery is a variable that topical use largely avoids, and that anyone with impaired copper regulation faces a categorically different risk calculus which brings us to safety
Rink C, Christoforidis G, Khanna S, Peterson L, Patel Y, Khanna S, Abduljalil A, Irfanoglu O, Machiraju R, Bergdall VK, Sen CK (2011) Tocotrienol vitamin E protects against preclinical canine ischemic stroke by inducing arteriogenesis
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Assoc.J.,2010, 4, 310-316 16
Discontinuation of medications that can inhibit enzymes involved in the -glutamyl cycle and that consume glutathione, aggressive treatment of associated risk factors such as malnutrition and supportive management
