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The broader pattern of GLP-1 drugs reducing addictive and compulsive behavior has shown up across multiple datasets, including a 606,000-veteran cohort published in BMJ earlier this year showing meaningful reductions in alcohol, nicotine, and opioid use disorder rates in GLP-1 users

To monitor ATP release in real time, we used sniffer patches 16 , composed of slowly-inactivating P2X 2 receptors 17 over-expressed in HEK293 cells, as a local ATP sensor