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ATP and its degradation product adenosine are themselves neurotransmitter molecules (termed purinergic transmission) that can also modify the pre- or postsynaptic cells response if the appropriate receptors are present

They found that although many regions of the brain have GLP-1 receptors, when the mice were dosed with the GLP-1R agonist semaglutide, the semaglutide ended up on only a fraction of the mouse brains GLP-1 receptors, mainly in the hypothalamus, brainstem, and septum

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GLP-1 RAs improved LVEF in individuals with acute myocardial infarction (AMI) (Class IV

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