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ADX47273 - CAS# 851881-60-2 0127 alkaline phosphatase (ALP)

ADX47273 - CAS# 851881-60-2 0127 alkaline phosphatase (ALP)

Name: ADX47273 - CAS# 851881-60-2 0127 alkaline phosphatase (ALP)
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ADX47273 - CAS# 851881-60-2 0127 alkaline phosphatase (ALP)ADX 47273, CAS No. 851881 60 2, is a potent and selective mGluR5 receptor PAM (positive allosteric modulator), EC50 = 0. 17 m, with no effect on other mGluR subtypes. In vivo, ADX47273 increased extracellular signal regulated kinase and cAMP responsive element binding protein phosphorylation in hippocampus and prefrontal cortex, both of which are critical for glutamate mediated signal transduction mechanisms. The mGluR (metabotropic glutamate

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Description

alkaline phosphatase (ALP)

de Alwis DP

The deleterious synergistic effect between ER-stress and ISRIB may be generally advantageous to kill cancer cells

is a brain penetrant

6(10):e25134

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