(R)-(+)-Etomoxir Sodium Salt Size:Solid 2 mg SRI-011381 hydrochloride promotes fibrillar Aβ

SRI-011381 hydrochloride promotes fibrillar Aβ clearance by macrophages

InChi: InChI=1S/C20H17FN2O3S/c1-14-12-16(15-8-4-2-5-9-15)13-18(19(14)21)20(24)22-23-27(25

Chemical Name: 1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3

Smiles: O=C(O[Na])[C@]1(CO1)CCCCCCOC1C=CC(Cl)=CC=1

random screening against the AMPK α1β1γ1 heterotrimer is performed and a new AMPK activator

(R)-(+)-Etomoxir Sodium Salt Size:Solid 2 mg SRI-011381 hydrochloride promotes fibrillar AβEtomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1 (CPT 1) on the outer face of the inner mitochondrial membrane. This prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria. This step is essential to the production of ATP from fatty acid oxidation. Etomoxir has also been identified as a direct agonist of PPAR.