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However, no randomized controlled trials have rigorously evaluated whether treatment of CHE reduces the risk of OHE or mortality [4]

Roitman, S., et al

Indiscriminate use of systemic antibiotics can increase skin colonisation, particularly with Candida , so should only be used where there is a clinical suspicion of infection [4]

Effector cells and target cells were mixed and cultured according to E:T = 1:1, 2:1, 5:1 or 10:1

Novo Nordisk also submitted a bid, but Metsera deemed it carried regulatory risks. However, Novo continued to submit unsolicited offers, raising its bid