DNA-PKCS Polyclonal Antibody, 50ul[BT-AP02678] Hepatocytes Alternative splicing of RNF111 results

Alternative splicing of RNF111 results in multiple transcript variants encoding distinct isoforms

Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS)

A pseudogene is located on chromosome 11

Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins

inducing changes in cell length that act to amplify sound levels

DNA-PKCS Polyclonal Antibody, 50ul[BT-AP02678] Hepatocytes Alternative splicing of RNF111 resultsPRKDC encodes the catalytic subunit of the DNA dependent protein kinase (DNA PK). It functions with the Ku70 Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein (protein kinase, DNA activated, catalytic polypeptide) encoded is a member of the PI3 PI4 kinase family.