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S3I-201 - CAS# 501919-59-1 254 (2015) Nat Chem Biol

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S3I-201 - CAS# 501919-59-1 254 (2015) Nat Chem BiolS3I 201, also known as NSC 74859, CAS No. 501919 59 1, is a cell permeable Stat3 inhibitor that binds to the Stat3 SH2 domain, prevents Stat3 phosphorylation activation, dimerization, and DNA binding. Product information CAS Number: 501919 59 1 Molecular Weight: 365. 36 Formula: C16H15NO7S Synonym: NSC 74859 Chemical Name: 2 hydroxy 4 (2 (tosyloxy)acetamido)benzoic acid Smiles: CC1C=CC(=CC=1)S(=O)(=O)OCC(=O)NC1=CC(O)=C(C=C1)C(O)=O InChiKey:

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(2015) Nat Chem Biol

7 uM (cellular inhibition of phospho-Ser916-PKD1 activity) [1] Target: PKD CID 2011756

(2011) Cancer Res

Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat

CAS Number: 112522-64-2

S3I-201 - CAS# 501919-59-1 254 (2015) Nat Chem BiolS3I 201, also known as NSC 74859, CAS No. 501919 59 1, is a cell permeable Stat3 inhibitor that binds to the Stat3 SH2 domain, prevents Stat3 phosphorylation activation, dimerization, and DNA binding. Product information CAS Number: 501919 59 1 Molecular Weight: 365. 36 Formula: C16H15NO7S Synonym: NSC 74859 Chemical Name: 2 hydroxy 4 (2 (tosyloxy)acetamido)benzoic acid Smiles: CC1C=CC(=CC=1)S(=O)(=O)OCC(=O)NC1=CC(O)=C(C=C1)C(O)=O InChiKey:

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