STF-083010 omide LDN-212320 (10 or 20 mg/kg

LDN-212320 (10 or 20 mg/kg

A selective IKK-2 inhibitor blocks NF- k B-dependent gene expression in interleukin-1ß-stimulated synovial fibroblasts

2014 Jun 7

47)55)62-41-23-39(57-11)46(32(8)60-41)63-40-22-38(56-10)42(31(7)59-40)51-33(9)52/h13-16

3)34-21(31)18-28-12-10-27-11-13-29(19-22(32)35-25(4

STF-083010 omide LDN-212320 (10 or 20 mg/kgSTF 083010, also known as IRE1 Inhibitor I, is an inhibitor of the IRE1 XBP1 pathway. Product information CAS Number: 307543 71 1 Molecular Weight: 317. 38 Formula: C15H11NO3S2 Chemical Name: N [(2 hydroxynaphthalen 1 yl)methylidene]thiophene 2 sulfonamide Smiles: OC1=CC=C2C=CC=CC2=C1C=NS(=O)(=O)C1=CC=CS1 InChiKey: TVIVJHZHPKNDAQ MHWRWJLKSA N InChi: InChI=1S C15H11NO3S2 c17 14 8 7 11 4 1 2 5 12(11)13(14)10 16 21(18,19)15 6 3 9 20 15 h1 10,17H b16 10+