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Leyden et al

Some studies have reported an association between 5ARI usage and depressive symptoms, though a definitive causal relationship has not been established [61]

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These changes may make it easier to lose fat when combined with proper nutrition, strength training, and adequate sleep, but results vary and weight loss is not guaranteed

Most patients experience no adverse effects, and when present, theyre typically mild and transient including temporary digestive changes as the gut adjusts, minor nausea (usually resolving within days), or altered bowel patterns during initial therapy