AEE788 igomycin A cell-based screen

cell-based screen

demonstrating potent antagonist activity

Wardlaw AJ

InChi: InChI=1S/C6H13NO3S/c7-5(6(9)10)4-11-3-1-2-8/h5

Topical CFTR Inhibitor II (10 μM) in mice rapidly and reversibly inhibits forskolin-induced hyperpolarization in nasal potential differences

AEE788 igomycin A cell-based screenAEE 788 is an orally bioavailable multiple receptor tyrosine kinase inhibitor. AEE788 inhibits phosphorylation of the tyrosine kinases of epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and vascular endothelial growth factor receptor 2 (VEGF2), resulting in receptor inhibition, the inhibition of cellular proliferation, and induction of tumor cell and tumor associated endothelial cell apoptosis. Check for