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Canadas Drug Agency (CDA-AMC) now recommends public coverage of Wegovy for patients with a BMI of 27 or greater and established cardiovascular disease

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FIGURE 1 Glucagon-Like Peptide-1 Receptor/Mitogen-Activated Protein Kinase Signal Pathway Mitogen-activated protein kinase (MAPK) belongs to silk/threonine protein kinase, mainly including extracellular signal-regulated kinase (Erk1/2), Jun N-terminal kinase (JNK) subfamily, p38 mitogen-activated protein kinase and ERK5 (Yue et al., 2019)

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Pyridoxine supports protein metabolism, neurotransmitter synthesis, and immune function