Trk B Polyclonal Antibody, 20ul[BT-AP09215] Antibody Development The human genome contains a

The human genome contains a pseudogene similar to the 3' half of this gene

These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity

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it is highly conserved among species

When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner

Trk B Polyclonal Antibody, 20ul[BT-AP09215] Antibody Development The human genome contains aNTRK2 encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.