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Apilimod dimesylate - CAS# 870087-36-8 077 including its NOX5 inhibitory activity

Apilimod dimesylate - CAS# 870087-36-8 077 including its NOX5 inhibitory activity

Name: Apilimod dimesylate - CAS# 870087-36-8 077 including its NOX5 inhibitory activity
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Apilimod dimesylate - CAS# 870087-36-8 077 including its NOX5 inhibitory activityApilimod dimesylate, CAS No. 870087 36 8, also known as STA 5326, is a IL 12 IL 23 inhibitor. Apilimod inhibits IL 12 and IL 23 production cytokines that are involved in autoimmune diseases through the prevention of nuclear translocation of c Rel. Synta Pharmaceuticals Corp is developing apilimod for the potential treatment of Crohn's disease (CD) and other autoimmune diseases. Preclinical studies demonstrated the successful inhibition of IL 12 and IL

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Description

including its NOX5 inhibitory activity

SR-01000909725-1

PubMed PMID: 29181125

a highly selective inhibitor of heat shock protein 90α and β

threonine and tyrosine kinases

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