Bay 60-7550 - CAS# 439083-90-6 Size:Solid 10 mg Smiles: CN1N=CC2=C1N=C(N)N=C2N1CCN(C[C@@H]1C)C(=O)NC1=CC=C(C=C1C)OC

Smiles: CN1N=CC2=C1N=C(N)N=C2N1CCN(C[C@@H]1C)C(=O)NC1=CC=C(C=C1C)OC

Smiles: CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CC1C=CC=CC=1)C(O)=O

5-dimethoxyphenyl]quinoline-3-carboxamide bis(methanesulfonic acid) trihydrate

A small-molecule inhibitor of the Wnt pathway (SM04690) as a potential disease modifying agent for the treatment of osteoarthritis of the knee

oral aministration of PD173074 blocks tumor growth similar to that seen with single-agent cisplatin administration

Bay 60-7550 - CAS# 439083-90-6 Size:Solid 10 mg Smiles: CN1N=CC2=C1N=C(N)N=C2N1CCN(C[C@@H]1C)C(=O)NC1=CC=C(C=C1C)OCBAY 60 7550 is a potent PDE2 inhibitor with IC50 values of 2. 0 nM (bovine) and 4. 7 nM (human). BAY 60 7550 antagonizes oxidative stress induced anxiety like behavioral effects in mice by increasing cGMP signaling. Phosphodiesterases (PDEs) are key regulatory enzymes of intracellular cAMP cGMP levels. These second messengers play important regulatory roles in controlling steroidogenesis in the adrenal. Disruption of PDEs has been associated with a