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DLK1 Monoclonal Antibody, 50ul Cell Culture Plates These kelch-like repeats promote substrate

SKU: 75231259311

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DLK1 Monoclonal Antibody, 50ul Cell Culture Plates These kelch-like repeats promote substrateThis gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child

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Description

These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex

Members of this family metabolize a wide variety of substrates

Tween and Triton X-100

the cell cycle is governed by cyclin-dependent protein kinases (CDKs)

resulting in its accumulation at intranuclear foci induced by DNA damage

DLK1 Monoclonal Antibody, 50ul Cell Culture Plates These kelch-like repeats promote substrateThis gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child

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