Jak2(Phospho-Tyr1008) Rabbit Polyclonal Antibody, 100ul Filtration Mutations in this gene cause

Mutations in this gene cause epidermolysis bullosa junctional Herlitz type

Additional transcript variants have been found

This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors

designated the Sec insertion sequence (SECIS) element

and is an important therapeutic target for the treatment of hypomotility disorders

Jak2(Phospho-Tyr1008) Rabbit Polyclonal Antibody, 100ul Filtration Mutations in this gene causeThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.