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Some of the existing trials have examined whether vitamin E supplements might slow the cognitive decline associated with certain neurodegenerative diseases, such as Parkinsons disease or Alzheimers disease, although few have conducted specific assessments of memory

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Although oxidative stress was defined originally as a balance between oxidants and antioxidants systems, an equilibrium among antioxidant strategies is needed to avoid the generation of oxidants and ROS ( SUPEROXIDE, HYDROGEN PEROXIDE, AND PEROXYNITRITE GENERATION Despite the fact that superoxide can be generated in extramitochondrial reactions, in most cell types mitochondria appear as the main source of superoxide generation