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In addition, artemisinin increases ROS levels, and FIN56 binds and activates squalene synthase to accumulate ROS (Kang et al., 2019), leading to the depletion of endogenous antioxidant CoQ10 and then inducing ferroptosis by lipid peroxidation

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doi: Pattani A

A 503b designation means the pharmacy operates as an outsourcing facility under more stringent FDA oversight than standard 503a compounding pharmacies