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ORY-1001 (RG-6016) - LSD1 Inhibitor. CAS# 1431326-61-2 60252 pAKT (S473) IC50 = 0

ORY-1001 (RG-6016) - LSD1 Inhibitor. CAS# 1431326-61-2 60252 pAKT (S473) IC50 = 0

Name: ORY-1001 (RG-6016) - LSD1 Inhibitor. CAS# 1431326-61-2 60252 pAKT (S473) IC50 = 0
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SKU: 54291201333
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SKU: 54291201333

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ORY-1001 (RG-6016) - LSD1 Inhibitor. CAS# 1431326-61-2 60252 pAKT (S473) IC50 = 0ORY 1001, CAS No. 1431326 61 2, is a highly potent and selective inhibitor of Lysine Specific Demethylase 1 (LSD1) with IC50 <20 nM. It is highly selective over related enzymes such as MAO A B. ORY 1001 affects AML stem cells, a sub population of cancer cells that has been proposed to be responsible for frequent relapses of the disease. It significantly reduces tumor cell load and increases survival time in mouse models of Acute Lymphoblastic

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Description

pAKT (S473) IC50 = 0

Epigenetic compounds library of Hypoxia Inducible Factor

Molecular Weight: 302

PubMed PMID: 22713795

TAE684 induces apoptosis and G1 phase arrest in NPM-ALK-expressing Ba/F3 cells and ALCL patient cell lines

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